The challenges faced by the people and society in India and its neighborhood are very similar in nature and is not defined by geopolitical boundaries. Some of these common challenges can be met collectively through application of science and technology. In our efforts to build and strengthen a partnership through science, technology and innovation with our neighboring countries, a “Science & Technology Minister’s Conclave” will be organized in the India International Science Festival 2017. This Conclave will provide an opportunity to exchange the scientific and technological priorities and challenges of some of our neighbouring countries that can help to develop a road map of S&T cooperation by developing human capacity and infrastructure. Based on the deliberations in the Conclave, the Ministry of Science and Technology is expected to devise and announce programmes of cooperation with the neighborhood countries.